Depression
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Clinical depression is a state of intense sadness, melancholia or despair. Some characters on Heroes either suffer from, or are rumored to suffer from depression.
About
Don't Look Back
Angela Petrelli visits her son Peter in the hospital. She reveals to him that Mr. Petrelli was diagnosed with major depressive disorder at age 23, and that he took his own life as a result.
One Giant Leap
Nathan Petrelli holds a press conference in order to gain positive publicity for his campaign. During the conference, he reveals that his father suffered from depression, and that it was the cause of his death. He also alienates Peter by claiming that Peter followed in his father's footsteps and attempted a depression-related suicide.
Nothing to Hide
Oliver Dennison sits on the veranda of the Petrellis' home, interviewing Nathan and his family for the New York Journal. Dennison pointedly asks the congressional candidate about being spotted with a blond woman in Las Vegas, and his subsequent disappearance. Thinking quickly, Peter lies to the reporter and tells him that Nathan was meeting with a depression expert on Peter's behalf.
Graphic Novel:How Do You Stop an Exploding Man?, Part 1
After his wife dies, Ted Sprague is left alone, depressed, enraged, and confused.
Run!
Zane Taylor doesn't know how to handle his newfound powers, and becomes scared and agitated.
Parasite
After Simone's death, Isaac becomes so despondent he turns his drug addiction.